Why can stomach bleeding occur with Zymbalta when you combine it with aspirin or NSAIDs?
I think the combination of these drugs take away the protective prostaglandins in the stomach that neutralize the hydrochloric acid in your stomach. I think Zymbalta and an NSAID or asprin together break down the prostaglandins so severely that this means open season for the stomach as far as acid is concerned…it can lead to peptic ulcers, which could put one at a very, very high risk for stomach bleeding.
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